Change the reapply mechanics from either Lifebane and/or dots from weapons like live poison mechanics. Meaning you can only reapply when the dot duration is over. In most cases even if you manage to kill a Sin, he will just hit you with a new lifebane poison for 5XX extra damage after his death. Even higher if he gets a new dot proc again off, that is can easily add up to something like 750-1k. I think a change would also help with the overall complain a lot have about disease. This does not change the thing with disease but atleast you can still walk with having more HP, instead of having disease and end up with like 1-5% HP(if you are lucky not to die) were you can do absolutely nothing. I am only talking about the damage ones here, not about enervating or disease or the poison weapon swap in general.
I also think this helps other weapons a lot because you barely see anything except dot. Pretty much every SB now is axe in using Dragonmight as Main. Most Nightshades I have seen are pierce. And even Tanks (2h) are having weapons with dots(Both feathers and crafted for the double dot effect).